Even with conventional treatment alone
Two-thirds of patients have HbA1c of 6.5% or less (JDS value)
More than half of our first-visit patients have HbA1c of 7% or more. We are visiting not only from Tokyo but also from all over the country. Most patients find no reliable diabetic specialist nearby, dislike insulin injections, or are not satisfied with the current treatment. Most of the first-time patients at our hospital are those who find the book of Director Suzuki at a bookstore, listen to rumors, search for their name on the Internet, and come to the hospital. Of course, nearby diabetics will also come to the hospital. (The figures in the figure below are displayed as JDS values. To see the NGSP values, add 0.4%.)
The pie chart below shows the distribution of HbA1c at the first visit and 6 months after taking the DPP4 inhibitor. Blue is HbA1c 6% or less, and orange is 6.1-6.4%. The blue color was more than half (57%) when taking the DPP4 inhibitor. 20% is orange. It will be 77% in total. In other words, three-quarters have HbA1c of less than 6.5%, achieving extremely good glycemic control. Perhaps this clinical result is one of the best in Japan. It is now much better than in 2008.
HbA1c at the first visit to our hospital. About two-thirds is 7% or more.
HbA1c after going to the hospital. Two-thirds is 6.5% or less.
As of May 2008, two-thirds of outpatients had HbA1c of 6.5% or less. We have provided a high level of medical care that can sufficiently reduce HbA1c to 6.5% or less with conventional treatment alone. At this time, I had not been treated with incretins, that is, DPP4 inhibitors or GLP1 derivatives. Even so, the reason why the treatment results were so excellent was the medical treatment with the cooperation of diabetes educators and different ideas for various outpatient treatments.
HbA1c can be lowered sufficiently with conventional therapies, but even lower with new drugs.
The figure below is a broken line graph of HbA1c at the first visit, HbA1c before the start of the DPP4 inhibitor, HbA1c 3 months after taking the DPP4 inhibitor, and HbA1c at 6 months. Since there were 33 patients whose HbA1c was less than 6.5% before taking the drug, we have compiled the data of those patients. Diabetes treatment is performed at a medical level that surprises everyone as to how much blood sugar control can be performed by patients who were difficult to treat at other medical facilities. You can see from this data that the 5% level of HbA1c is normal in our hospital. Cited Paper Endocr Res. 2012; 37 (4): 175-81. Doi: 10.3109 / 07435800.2012.662664. Epub 2012 May 23. A new preventive strategy for hypoglycemia incorporated added food diet in patients with type 2 diabetes who received sitagliptin therapy. Meguro S, Sano M, Kawai T, Matsuhashi T, Mogi S, Fukuda K, Itoh H, Suzuki Y